Positive Epstein-Barr Virus and Cytomegalovirus IgM Assays in Primary HIV Infection
Positive Epstein-Barr Virus and Cytomegalovirus IgM Assays in Primary HIV Infection
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DOI：
10.1002/jmv.22109
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发表时间：
2011-08-01
影响因子：
12.7
通讯作者：
Robertson, Peter W.
中科院分区：
文献类型：
--
作者：
Post, Jeffrey J.;Chan, Mun Khin;Robertson, Peter W.
We report three cases with misleading cytomegalovirus (CMV) or Epstein-Barr virus (EBV) immunoglobulin M (IgM) results during primary human immunodeficiency virus (HIV) infection. We determined the rate of positive anti-CMV IgM assays or anti-EBV capsid antigen IgM assays in sera from a group of well-characterized subjects with primary HIV infection as 2.9% (1/35; 95%CI: 0.15-16.6%) for each infection. The rate of positive anti-EBV capsid antigen IgM assays in subjects with positive hepatitis A virus IgM assays was 30% (6/20; 95%CI: 14.6-51.9%). Clinicians need to consider the limitations of IgM assays for diagnosis of herpesvirus infections, and consider testing for other infections with overlapping clinical manifestations. J. Med. Virol. 83:1406-1409, 2011. (C) 2011 Wiley-Liss, Inc.
