Management of Urosepsis in 2018
Management of Urosepsis in 2018
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DOI：
10.1016/j.euf.2018.11.003
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发表时间：
2019-01-01
影响因子：
5.4
通讯作者：
Wagenlehner, Florian M. E.
中科院分区：
文献类型：
--
作者：
Bonkat, Gernot;Cai, Tomasso;Wagenlehner, Florian M. E.
尽管有最佳的治疗，尿脓毒症仍然有很高的发病率和死亡率。最近引入了更新的脓毒症定义和分类系统。尿脓毒症的治疗包括四个主要方面：（1）早期诊断，（2）早期经验性静脉抗菌治疗，（3）识别和控制并发因素，（4）特异性脓毒症治疗。快速序贯器官衰竭评估正在取代全身炎症反应综合征评分，用于快速识别urosepsis.Patient摘要：尿脓毒症是一种严重的，危及生命的并发症，源于尿路感染。由于尿脓毒症具有非常高的死亡率，重要的是要迅速发现并迅速开始适当的治疗。尿路疾病的成像已被证明是有用的，在降低死亡率从尿脓毒症，在未来的微生物学技术也可能证明是有用的。鉴于尿脓毒症的严重性和相关风险，需要做出巨大努力，通过适当的预防措施来预防医院中的高风险感染，例如尽可能早期移除所使用的导管。(c)2018年欧洲泌尿外科协会。Elsevier B.V.出版，保留所有权利。
Despite optimal treatment, urosepsis has still high morbidity and mortality rates. An updated definition and classification system for sepsis have recently been introduced. Management of urosepsis comprises four major aspects: (1) early diagnosis, (2) early empiric intravenous antimicrobial treatment, (3) identification and control of complicating factors, and (4) specific sepsis therapy. The quick sequential organ failure assessment is replacing the systemic inflammatory response syndrome scoring for rapid identification of patients with urosepsis.Patient summary: Urosepsis is a serious, life-threatening complication of infections originating from the urinary tract. As urosepsis has a very high mortality rate, it is important that is quickly spotted and that appropriate treatment is swiftly begun. Imaging of urinary tract disorders has been shown to be useful in decreasing mortality from urosepsis, and in the future microbiology techniques may also prove useful. Given the severity of urosepsis and the associated risks, large efforts need to be made to prevent high-risk infections in hospitals with appropriate prevention measures, such as the early removal of catheters used whenever possible. (c) 2018 European Association of Urology. Published by Elsevier B.V. All rights reserved.