A powerful cascade approach for expeditious synthesis of trifluoromethylated furans.
A powerful cascade approach for expeditious synthesis of trifluoromethylated furans.
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DOI：
10.1021/ol2022092
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发表时间：
2011-09
期刊：
影响因子：
5.2
通讯作者：
Yao Wang;Yong-Chun Luo;Xiu-Qin Hu;Peng‐Fei Xu
中科院分区：
文献类型：
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作者：
Yao Wang;Yong-Chun Luo;Xiu-Qin Hu;Peng‐Fei Xu
已经开发出一种合成三氟甲基化呋喃的有效方法。该方法操作简单，底物范围广泛，并且适合使用三氟乙酸酐进行放大。同时，该策略不仅为合成三氟甲基呋喃提供了一种通用的方法，而且为探索三氟乙酸酐的新反应性提供了一种新方法。
A powerful approach to synthesize trifluoromethylated furans has been developed. The method is operationally simple, broad in substrate scope, and amenable to scale-up using trifluoroacetic anhydride. Meanwhile, the strategy not only provided a versatile approach to synthesize trifluoromethylated furans but also provides a new method for exploring the new reactivity of trifluoroacetic anhydride.