PHYSIOLOGY OF PERIPHERAL NEURONS INNERVATING OTOLITH ORGANS OF SQUIRREL-MONKEY .1. RESPONSE TO STATIC TILTS AND TO LONG-DURATION CENTRIFUGAL FORCE
PHYSIOLOGY OF PERIPHERAL NEURONS INNERVATING OTOLITH ORGANS OF SQUIRREL-MONKEY .1. RESPONSE TO STATIC TILTS AND TO LONG-DURATION CENTRIFUGAL FORCE
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DOI：
10.1152/jn.1976.39.5.970
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发表时间：
1976-01-01
影响因子：
2.5
通讯作者：
GOLDBERG, JM
中科院分区：
文献类型：
--
作者：
FERNANDEZ, C;GOLDBERG, JM
在巴比妥酸盐麻醉的松鼠猴（Saimiri sciureus）上研究了外周耳石神经元。每个单元的最敏感轴由功能极化矢量定义。将单位分配给上级（SN）或下级（IN）前庭神经。在一些动物中，在SN切片后研究IN单位。SN单位的矢量位于椭圆囊平面附近，IN矢量位于囊状平面附近。静息放电平均为60峰/秒，灵敏度为35峰/秒·克。IN单位与向上（+Z）向量有显着较高的静息放电比-Z单位，其特征在于更线性的力-反应关系。对于有规律放电的单位，静息放电与敏感性之间存在较强的正相关。一个较弱的关系被发现在不规则的单位。在不规则单位中，对长时间刺激的适应更为明显。规则单位的兴奋性反应几乎总是大于抑制性反应。在不规则单元的动态响应中可以看到类似的不对称性;静态响应不对称性更易变。
Peripheral otolith neurons were studied in the barbiturate-anesthetized squirrel monkey (Saimiri sciureus). Each unit''s most sensitive axis was defined by a functional polarization vector. Units were assigned to the superior (SN) or inferior (IN) vestibular nerves. In some animals, IN units were studied after section of the SN. Vectors for SN units lay near the utricular plane, IN vectors near the saccular plane. The resting discharge averaged 60 spikes/s, the sensitivity 35 spikes/s-g. IN units with upwardly directed (+Z) vectors had substantially higher resting discharges than did -Z units and were characterized by more linear force-response relations. A strong positive relation existed between resting discharge and sensitivity for regularly discharging units. A weaker relation was found in irregular units. Adaptation to prolonged stimulation was more conspicuous in irregular units. Excitatory responses of regular units were almost always larger than are inhibitory responses. A similar asymmetry was seen in the dynamic responses of irregular units; static response asymmetries were more variable.