Quality of life in chronic hemodialysis patients in Russia.
Quality of life in chronic hemodialysis patients in Russia.
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DOI：
10.1111/j.1542-4758.2006.00108.x
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发表时间：
2006-07-01
期刊：
影响因子：
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通讯作者：
Vasilieva, Irina A
中科院分区：
文献类型：
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作者：
Vasilieva, Irina A
本横断面研究的目的是将俄罗斯血液透析（HD）患者的健康相关生活质量（HRQOL）与一般人群和国际数据进行比较，并确定影响HRQOL的因素。来自6个透析中心的1447例HD患者进行了研究（576名男性，年龄43.5 +/- 12.5岁，HD病程55.0 +/- 47.2个月）。健康相关生活质量采用SF-36进行评估。采用自评抑郁量表（W. Zung）、状态-特质焦虑量表和神经衰弱水平量表。血液透析患者在大多数SF-36量表中的得分明显低于一般俄罗斯人群。唯一的例外是心理健康得分，它甚至比一般人群要好。HD患者身体成分评分（PCS）均值为36.9 +/- 9.7，精神成分评分（MCS）均值为44.2 +/- 10.5。多元线性回归分析显示，年龄增加、HD病程、抑郁程度、近6个月住院天数是低PCS与低血清白蛋白水平的显著独立预测因子。随着年龄的增长，HD病程、抑郁程度、特质焦虑和虚弱程度的增加，MCS降低也是一个预测因素。据我们所知，这是第一个报道使用SF-36对俄罗斯HD患者进行大样本HRQOL的研究。与一般人群相比，俄罗斯HD患者在大多数SF-36量表上的得分明显较低，尤其是在身体方面。平均PCS和MCS与欧洲HD患者的数据相当。许多人口统计学、临床和心理变量影响HRQOL。
The aim of this cross-sectional study was to compare health-related quality of life (HRQOL) of Russian hemodialysis (HD) patients with the general population and international data, and to determine factors influencing HRQOL. One thousand forty-seven HD patients from 6 dialysis centers were studied (576 male, age 43.5 +/- 12.5 years, HD duration 55.0 +/- 47.2 months). Health-related quality of life was evaluated by SF-36. Self-appraisal Depression Scale (W. Zung), State-Trait Anxiety Inventory, and Level of Neurotic Asthenia Scale were used. Hemodialysis patients scored significantly lower than the general Russian population in the majority of SF-36 scales. The only exception was the Mental Health score, which was even better than the general population. The Mean physical component score (PCS) of HD patients was 36.9 +/- 9.7, and the mental component score was (MCS) 44.2 +/- 10.5. In multiple linear regression analysis, increasing age, HD duration, depression level and number of days of hospitalization in the past 6 months were significant independent predictors of low PCS along with a low level of serum albumin. Advancing age was also a predictive factor for low MCS along with increase of HD duration, depression level, trait anxiety, and level of asthenia. As far as we know, this is the first study to report on HRQOL of a large sample of Russian HD patients performed using SF-36. Compared with the general population, Russian HD patients had significantly lower scores on the majority of SF-36 scales, especially in the physical domain. The mean PCS and MCS were comparable with European data for HD patients. A number of demographic, clinical, and psychological variables affect HRQOL.