Inclusive separation of acetophenone from petrochemical by‐product with 1‐phenylethanol via noncovalent interactions
Inclusive separation of acetophenone from petrochemical by‐product with 1‐phenylethanol via noncovalent interactions
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DOI：
10.1002/aic.14474
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发表时间：
2014-08
期刊：
影响因子：
3.7
通讯作者：
K. Chai;Hongbing Ji
中科院分区：
文献类型：
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作者：
K. Chai;Hongbing Ji
利用β-环糊精（β-CD）对苯乙酮的选择性亲和作用，对炼油厂副产物1-苯基乙醇和苯乙酮的混合物进行了分离研究。为了证明β-CD在分离苯乙酮和1-苯乙醇中的潜在应用，从热力学和构象角度比较了β-CD与苯乙酮和1-苯乙醇的非共价相互作用。基于β-CD的选择性非共价结合特性，建立了多元共沉淀分离技术，并得到了严格的证明。在优化条件下，苯乙酮/1-苯乙醇等摩尔二元混合物可实现分离，分离因子>37。对于含有74.93wt%苯乙酮、17.79wt% 1-苯基乙醇等微量化合物的石化副产品，扩大分离规模，复合物中苯乙酮含量可达99.2%，回收两次后β-CD分离效率保持稳定。© 2014美国化学工程师学会AIChE J，60：2962-2975，2014
Separation of the barely studied mixture of acetophenone and 1-phenylethanol, a typical by-product obtained by oil refinery plant, based on the preferential affinity of β-cyclodextrin (abbreviated as β-CD) for acetophenone is focused. To demonstrate the potential application of β-CD for separation of acetophenone from 1-phenylethanol, the noncovalent interactions of β-CD with acetophenone and 1-phenylethanol were compared from thermodynamic and conformational points of view. For the purpose of separation, a multicomponent coprecipitation technique has been established based on the selective noncovalent binding property of β-CD, which has been proved rigorously. Under the optimized conditions, the acetophenone/1-phenylethanol equimolar binary mixture can be separated with a separation factor >37. For the petrochemical by-product, which contains 74.93 wt % of acetophenone, 17.79 wt % of 1-phenylethanol, and other minor compounds, expanding the separation scale, content of acetophenone in complex can get 99.2%, and the separation efficiency of β-CD kept stable after recycling twice. © 2014 American Institute of Chemical Engineers AIChE J, 60: 2962–2975, 2014