The Symptom Cluster of Sleep, Fatigue and Depressive Symptoms in Breast Cancer Patients: Severity of the Problem and Treatment Options.
The Symptom Cluster of Sleep, Fatigue and Depressive Symptoms in Breast Cancer Patients: Severity of the Problem and Treatment Options.
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DOI：
10.1016/j.ddmod.2011.05.001
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发表时间：
2011
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乳腺癌是女性最常见的癌症。乳腺癌是乳腺癌患者的一个重要问题，影响20%至70%的新诊断或最近治疗的癌症患者。疼痛、疲劳、焦虑和抑郁也是乳腺癌的常见症状，通常与失眠症状群同时发生，相互加重，降低生活质量（QOL）。目前还没有针对癌症患者的睡眠药物的临床试验。另一方面，认知行为心理疗法在缓解乳腺癌患者的痛苦症状方面取得了一些最积极的成果，但即使是这些研究也没有针对症状群。需要探索药物和非药物治疗。这可能是一个组合的药物和行为治疗是最有效的。简而言之，需要更多的研究来充分了解和治疗乳腺癌中的失眠、疲劳、疼痛、抑郁和焦虑症状群。
Breast cancer is the most commonly diagnosed cancer in women. Insomnia is a significant problem in breast cancer patients, affecting between 20% to 70% of newly diagnosed or recently treated cancer patients. Pain, fatigue, anxiety, and depression are also common conditions in breast cancer and often co-occur with insomnia in symptom clusters, exacerbating one another, and decreasing quality of life (QOL). There have been no clinical trials of drugs for sleep in cancer. Cognitive behavioral psychotherapies on the other hand, have shown some of the most positive results in alleviating the distressing symptoms that often accompany the breast cancer experience, but even these studies have not targeted the symptom cluster. Pharmacological as well as non-pharmacological treatments need to be explored. It might be that a combined pharmacological and behavioral treatment is most efficacious. In short, substantially more research is needed to fully understand and treat the symptom cluster of insomnia, fatigue, pain, depression and anxiety in breast cancer.