Endogenous opiate involvement in acute and chronic stress-induced changes in plasma LH concentrations in the male rat.
Endogenous opiate involvement in acute and chronic stress-induced changes in plasma LH concentrations in the male rat.
复制标题
内源性阿片类药物参与急性和慢性应激引起的雄性大鼠血浆 LH 浓度变化。
DOI：
10.1016/0024-3205(84)90285-6
复制
发表时间：
1984
期刊：
影响因子：
6.1
通讯作者：
Joseph Meites
中科院分区：
文献类型：
--
作者：
Karen P. Briski;Kathleen M. Quigley;Joseph Meites
The present study was carried out to examine the possible role of the endogenous opioid peptides (EOP's) on the pituitary luteinizing hormone (LH) response to both acute and chronic stress and to food deprivation. Thirty minutes after acute (2 min.) exposure to ether, plasma LH levels were elevated compared to controls; morphine (MOR) treatment prior to stress prevented this response. More prolonged etherization (15 minutes) significantly depressed circulating LH, whereas naltrexone (NALT), a specific opiate antagonist, reversed this decline. Immobilization for 8 hours resulted in a significant initial increase in LH release, followed by a decline toward baseline levels. Naltrexone treatment increased the magnitude of the acute LH rise, and attenuated the subsequent decrease in plasma LH.
