Comparison of CT scan and MRI findings in the diagnosis of Japanese encephalitis
Comparison of CT scan and MRI findings in the diagnosis of Japanese encephalitis
复制标题
DOI：
10.1016/s0022-510x(99)00318-4
复制
发表时间：
2000-03-01
影响因子：
4.4
通讯作者：
Misra, UK
中科院分区：
文献类型：
--
作者：
Kalita, J;Misra, UK
流行性乙型脑炎是最常见的地方性脑炎，但关于其放射学变化的研究很少，而且这些研究都是基于相对较少的患者。本研究的目的是比较乙脑的CT扫描和MRI表现，并将其与报告的组织病理学结果相关联。42例乙脑患者进行了详细的神经系统检查。38例行头颅CT扫描，31例行MRI扫描。对急性期和恢复期血清进行血凝抑制试验。将CT扫描与MRI检查结果进行了比较。28例患者均行CT和MRI检查。21例CT异常，其中丘脑低密度15例，中脑、基底节低密度各1例，脑水肿4例，皮质萎缩伴脑室扩大2例。31例MRI均异常，其中17例CT扫描正常。头颅MRI除2例患者外，其余患者均显示丘脑T-1混合信号或低信号病变，T-2高信号或混合信号病变。MRI病变还出现在基底神经节11例、中脑18例、脑笔8例、小脑和大脑皮质各6例以及皮质下白色物质2例。MRI在显示丘脑和丘脑外异常方面比CT更敏感。丘脑改变对乙脑的诊断有一定的帮助，尤其是在流行区。(C)2000 Elsevier Science B. V.保留所有权利。
Japanese encephalitis (JE) is the commonest endemic encephalitis but there are very few studies on the radiological changes and these are based on relatively small number of patients. The present study aims at comparing the CT scan and MRI findings in JE and correlate these with the reported histopathological findings. Forty two patients with JE were subjected to detailed neurological examination. Cranial CT scan was carried out in 38 and MRI scan in 31 patients. Haemagglutination inhibition test was carried out in the acute and convalescent sera. The CT scan and MRI findings have been compared. Both CT scan and MRI were available in 28 patients. In 21 patients, CT scans were abnormal and changes included thalamic hypodensity in 15, midbrain and basal ganglia hypodensity in 1 patient each, cerebral oedema in 4 and cortical atrophy with ventricular dilatation in 2 patients. MRI however was abnormal in all 31 patients including 17 with normal CT scan. Cranial MRI revealed either mixed intensity or hypointense lesion on T-1 and hyperintense or mixed intensity lesion on T-2 in thalami in all except two patients. The MRI lesions were also noted in basal ganglia in 11, midbrain in 18, pens in 8, cerebellum and cerebral cortex in 6 patients each and subcortical white matter in 2 patients. MRI was more sensitive than CT scan in revealing thalamic and extrathalamic abnormalities. Thalamic changes may be helpful in the diagnosis of JE especially in endemic area. (C) 2000 Elsevier Science B.V. All rights reserved.