Prevalence of amblyopia and its association with refraction in Chinese preschool children aged 36-48 months

Prevalence of amblyopia and its association with refraction in Chinese preschool children aged 36-48 months
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中国36-48月龄学龄前儿童弱视患病率及其与屈光的关系

DOI:
10.1136/bjophthalmol-2016-310083
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发表时间:
2018-06-01
影响因子:
4.1
通讯作者:
Liu, Hu
Liu, Hu
中科院分区:
医学2区
文献类型:
--
作者:
Huang, Dan;Chen, Xuejuan;Liu, Hu

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目的了解中国学龄前儿童弱视的患病率及其与屈光的关系。方法于2015年对中国南京市雨花台地区36-48月龄儿童进行基于人群的横断面研究——雨花台儿童眼病研究。对1695名符合条件的儿童进行了视力测量。结果在1695名受试者中,有25名儿童出现明显弱视(1.47%,95% CI 0.90% ~ 2.05%),其中双侧弱视11名,单侧弱视14名。弱视患病率无性别差异(p=0.77)。弱视患儿中有明显屈光不正22例(88.0%),斜视6例(24.0%)。在多变量分析中,弱视与远视显著相关(+2.00 dioptres (D);OR为8.81,95%CI为3.27 ~ 23.69
Purpose To determine the prevalence of amblyopia and its association with refraction in Chinese preschool children.Methods The Yuhuatai Pediatric Eye Disease Study, a cross-sectional, population-based study, was conducted in children aged 36-48 months in Yuhuatai District, Nanjing, China, in 2015. Visual acuity was measured in 1695 eligible children.Results Of the 1695 subjects, manifested amblyopia was detected in 25 children (1.47%, 95% CI 0.90% to 2.05%), including 11 and 14 with bilateral and unilateral amblyopia, respectively. Amblyopia prevalence did not differ by gender (p=0.77). Significant refractive errors were found in 22 (88.0%) of children with amblyopia, and strabismus was found in 6 (24.0%) children with amblyopia. In multivariate analysis, amblyopia was significantly associated with hyperopia (+2.00 dioptres (D); OR 8.81, 95%CI 3.27 to 23.69, p