Chemistry of renieramycins.: Part 5.: Structure elucidation of renieramycin-type derivatives O, Q, R, and S from Thai marine sponge Xestospongia species pretreated with potassium cyanide

Chemistry of renieramycins.: Part 5.: Structure elucidation of renieramycin-type derivatives O, Q, R, and S from Thai marine sponge Xestospongia species pretreated with potassium cyanide
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DOI:
10.1021/np030534o
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发表时间:
2004-06-01
影响因子:
5.1
通讯作者:
Saito, N
Saito, N
中科院分区:
生物学2区
文献类型:
--
作者:
Amnuoypol, S;Suwanborirux, K;Saito, N

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从经氰化钾预处理的海绵Xestospongia sp.中分离得到4个次要的雷尼霉素类衍生物,包括雷尼霉素0(1 o)和Q-S(1 q-s)。通过与最近报道的雷那霉素M(1 m)和N(1 n)的光谱数据比较,确定了它们的结构。还描述了转化和细胞毒性测量的结果。
Four minor renieramycin-type derivatives, including renieramycins 0 (1o) and Q-S (1q-s), were isolated from the sponge Xestospongia sp. pretreated with potassium cyanide. Their structures were elucidated by comparison of spectral data with those of recently reported renieramycins M (1m) and N (1n). The results of transformation and cytotoxicity measurements are also described.