The effects of examination stress on salivary cortisol, immunoglobulin A, and chromogranin A in nursing students
The effects of examination stress on salivary cortisol, immunoglobulin A, and chromogranin A in nursing students
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DOI：
10.2220/biomedres.29.221
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发表时间：
2008-08-01
影响因子：
1.2
通讯作者：
Yamaguchi, Yukari
中科院分区：
文献类型：
--
作者：
Takatsuji, Koichi;Sugimoto, Yoshie;Yamaguchi, Yukari
本研究旨在探讨考试压力对护生唾液皮质醇、免疫球蛋白A（伊加）及嗜铬粒蛋白A（CgA）的影响。在检查前和检查后1小时以及检查后2小时，从15名健康女性中采集唾液样本。唾液皮质醇，伊加和CGA浓度测定酶联免疫吸附试验。伊加和CgA浓度在检查后即刻显著升高（P < 0.05），2h后下降（P <0.05）。检查前后唾液皮质醇浓度无显著性差异。这些发现表明，由于检查引起的急性应激与唾液伊加和CgA升高有关，但与皮质醇无关。
This study aimed to assess the effects of examination stress on salivary cortisol, immunoglobulin A (IgA), and chromogranin A (CgA) in nursing students. Saliva samples were collected from 15 healthy females before and immediately after the one-hour examination, and two hours after the examination. Salivary cortisol, IgA, and CgA concentrations were determined by enzyme-linked immunosorbent assay. Both IgA and CgA concentrations statistically increased immediately after the examination (P < 0.05) and decreased two hours after the examination. No significant differences were observed between before and after the examination in the salivary cortisol concentration. These findings suggest that the acute stress due to the examination is associated with raised salivary IgA and CgA, but not cortisol.