Mechanistic understanding of the interaction of cells with nanostructured surfaces within the framework of biological functions
Mechanistic understanding of the interaction of cells with nanostructured surfaces within the framework of biological functions
复制标题
在生物功能框架内对细胞与纳米结构表面相互作用的机制理解
DOI：
10.1080/10667857.2023.2216529
复制
发表时间：
2023
影响因子：
3.1
通讯作者：
Boriek, Aladin M.
中科院分区：
文献类型：
--
作者：
Misra, R.D.K.;Boriek, Aladin M.
纳米结构表面与细胞的相互作用是复杂的，并且通过影响细胞的粘附、迁移、增殖和分化而对细胞的行为产生深远的影响。我们的研究强调了纳米结构和微结构表面对生物功能的对比效应。这种对比效应包括纳米级表面的物理和化学属性与微米级对应物相比的相对影响。这些属性通过调节细胞粘附、细胞增殖和功能蛋白质的合成导致生物纳米界面处的细胞活性改变。纳米结构引起的物理和化学变化可能会促进细胞粘附，而不会在表面上引入化学功能。这代表了在生物纳米表面指导细胞功能定制之外的重大进步。这将使人们更好地理解生物/非生物界面的合理设计，从而促进最佳的生物反应，从而开发新的生物医学技术。
The interaction of nanostructured surfaces with cells is complex and has a profound impact on the behaviour of cells by influencing their adhesion, migration, proliferation, and differentiation. Our studies highlighted the contrasting effects of nanostructured and microstructured surfaces on biological functions. Such contrasting effects include the relative influence of physical and chemical attributes of the nanoscale surface compared to the microscale counterpart. These attributes lead to an altered cellular activity at the bio-nano interface through modulating cell adhesion, proliferation of cells and synthesis of functional proteins. Physical and chemical changes induced by the nanostructure are likely to promote cell adhesion, without introducing chemical functionalities on the surface. This represents a significant advance beyond guiding the tailoring of cellular functionality at the bio-nano surface. This would yield an improved understanding of a rational design of biotic/abiotic interfaces that can promote optimal biological responses, leading to the development of new biomedical technologies.
X80自保护药芯焊缝金属应变时效脆化行为
DOI：
--
发表时间：
2023
期刊：
Materials technology (New York, N.Y.)
影响因子：
--
作者：
Lei Guo;X. Su;L. Dai;Leilei Wang;Qiaofei Sun;Chaohai Fan;Yalei Wang;Xueda Li
通讯作者：
Xueda Li
强塑性应变制备超细晶含钒低碳钢的微观结构稳定性
DOI：
--
发表时间：
2001
期刊：
影响因子：
--
作者：
Kyung;Yong;D. Shin
通讯作者：
D. Shin