Photoredox Catalysis Mediated Application of Methyl Fluorosulfonyldifluoroacetate as the CF2CO2R Radical Source.
Photoredox Catalysis Mediated Application of Methyl Fluorosulfonyldifluoroacetate as the CF2CO2R Radical Source.
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DOI：
10.1021/acs.orglett.6b02580
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发表时间：
2016-09
期刊：
影响因子：
5.2
通讯作者：
Wei Yu;Xiuhua Xu;F. Qing
中科院分区：
文献类型：
--
作者：
Wei Yu;Xiuhua Xu;F. Qing
报道了三氟甲基化试剂氟磺酰二氟乙酸甲酯（FO_2SCF_2CO_2Me，陈氏试剂）在可见光光氧化还原条件下作为甲氧羰基二氟甲基化试剂的新应用。FO2SCF2CO2Me与未活化的烯烃、苯乙烯或杂芳烃的可见光诱导反应提供了多种甲氧羰基二氟甲基化产物。
A new application of trifluoromethylating reagent, methyl fluorosulfonyldifluoroacetate (FO2SCF2CO2Me, Chen's reagent), as the carbomethoxydifluoromethylating reagent under visible light photoredox conditions is reported. The visible-light-induced reaction of FO2SCF2CO2Me with unactivated alkenes, styrenes, or heteroarenes affords a variety of carbomethoxydifluoromethylated products.