Multi-azole resistant Aspergillus fumigatus harboring Cyp51A TR46/Y121F/T289A isolated in Japan

Multi-azole resistant Aspergillus fumigatus harboring Cyp51A TR46/Y121F/T289A isolated in Japan
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DOI:
10.1016/j.jiac.2016.01.015
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发表时间:
2016-07-01
影响因子:
2.2
通讯作者:
Kamei, Katsuhiko
Kamei, Katsuhiko
中科院分区:
医学4区
文献类型:
--
作者:
Hagiwara, Daisuke;Takahashi, Hiroki;Kamei, Katsuhiko

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携带TR46/Y121F/T289A的多唑耐药烟曲霉菌于2013年12月从日本患者体内分离到。这种毒株与在法国和德国临床分离的毒株属于同一个Glade。携带这种突变的烟曲霉菌可能会迅速扩散到欧亚大陆以外的地方。(C)2016年日本化疗学会和日本传染病协会。爱思唯尔有限公司出版。保留所有权利。
Multi-azole resistant Aspergillus fumigatus carrying TR46/Y121F/T289A was isolated from a patient in Japan in Dec 2013. This strain grouped into the same Glade of the ones which were clinically isolated in France and Germany. A. fumigatus harboring this mutation could be rapidly diffused outside the Eurasian continent. (C) 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.