Diastereoselective Oxidative Cross-Coupling Reactions of Chiral Alkylbenzenes with Arenes and Silyl Nucleophiles
Diastereoselective Oxidative Cross-Coupling Reactions of Chiral Alkylbenzenes with Arenes and Silyl Nucleophiles
复制标题
手性烷基苯与芳烃和甲硅烷基亲核试剂的非对映选择性氧化交叉偶联反应
作者：
D. Nitsch;A. Pöthig;T. Bach
手性二、三甲氧基取代烷基苯与芳烃发生氧化交叉脱氢偶联反应，与硅基亲核试剂发生氧化偶联反应，产率适中至良好(41-99%)，具有显著的非对映选择性(DR=71：29~95：5)。
Chiral di- and trimethoxysubstituted alkylbenzenes underwent oxidative cross-dehydrogenative coupling reactions with arenes and related oxidative coupling reactions with silyl nucleophiles in moderate to good yields (41–99%) and with significant diastereoselectivities (dr = 71:29 to >95:5).