Conducting polymer nanowires for chemiresistive and FET-based bio/chemical sensors
Conducting polymer nanowires for chemiresistive and FET-based bio/chemical sensors
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DOI：
10.1039/b915717d
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发表时间：
2010-01-01
影响因子：
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通讯作者：
Myung, Nosang V.
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文献类型：
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作者：
Hangarter, Carlos M.;Bangar, Mangesh;Myung, Nosang V.
导电聚合物纳米结构是新兴材料，由于其化学敏感性和生物相容性，在电导/场效应晶体管（FET）生物/化学传感器方面具有巨大潜力。在此，我们回顾了基于聚合物纳米线的传感器的最新进展，并讨论了几个里程碑和持续挑战的影响。特别关注器件制造、纳米结构性能增强和功能化方案。已经针对单纳米线器件开发了多种组装和集成技术，但仍需要取得重大进展来提高可扩展性和可制造性。未来的工作应集中在高通量方法上，这些方法能够对导电聚合物纳米线和导电聚合物纳米结构的异质高密度阵列进行组合筛选，并针对目标分析物进行确定性定制。导电聚合物纳米线的空间和时间分辨率以及灵敏度增强的起源得到了解决。功能化路线又增加了生物传感器的复杂性，并在纳米传感器性能和设备制造的背景下进行讨论。
Conducting polymer nanostructures are emerging materials with tremendous potential for conductometric/field effect transistor (FET) bio/chemical sensors because of their chemical sensitivity and biocompatibility. Herein, we review recent developments in conducting polymer nanowire-based sensors and discuss the impact of several milestones and continuing challenges. Particular attention is given to device fabrication, nanostructure performance enhancement, and functionalization schemes. Several assembly and integration techniques have been developed for single nanowire devices but significant progress is still needed to improve scalability and manufacturability. Future work should focus on high throughput approaches that enable combinatorial screening of conducting polymer nanowires and heterogeneous, high density arrays of conducting polymer nanostructures, deterministically tailored for targeted analytes. The spatial and temporal resolution of conducting polymer nanowires is addressed along with the origin of the sensitivity enhancement. Functionalization routes add another degree of complexity for biosensors and are discussed in the context of nanosensor performance and device fabrication.