Birth and Future of Multiscale Modeling for Macromolecular Systems (Nobel Lecture)
Birth and Future of Multiscale Modeling for Macromolecular Systems (Nobel Lecture)
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DOI：
10.1002/anie.201403691
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发表时间：
2014-09-15
影响因子：
16.6
通讯作者：
Levitt, Michael
中科院分区：
文献类型：
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作者：
Levitt, Michael
获得诺贝尔奖是一次独特而奇妙的经历，没有人能做好准备，也没有人知道会发生什么。从一个普通人，辛辛苦苦地解决摆在我们面前的问题，瞬间转变为一个象征，一个名人，这是一个了不起的现象。一方面，一个成熟的人可能会对他们在转型之前的生活方式相当满意，因此希望事情像以前一样继续下去。另一方面，任何科学家都意识到榜样对他们整个职业生涯的重要性，因此想要延续这一传统，为子孙后代树立这样的榜样。这是我现在面临的一个难题，可能需要数十年才能解决。诺贝尔奖演讲与其他讲座的不同之处在于，它结合了过去、现在和未来，面向从感兴趣的学校儿童到专家同事的不同听众。写下这样的演讲往往会遵循数百年来科学论文写作的传统，这可能会错过实际演讲的一些新鲜感。面对这一挑战，我决定以我的诺贝尔奖演讲为基础，以幻灯片为图形，撰写这篇书面演讲。主要测试提供了一个简单的叙述，而数字图例有助于更具体的评论和讨论。
Winning the Nobel Prize is a unique and marvelous experience that no one can prepare for or in any way know what to expect. The instantaneous transformation from an ordinary human, toiling away to solve the problems that come before us, into being a symbol, a celebrity, is a remarkable phenomenon. On the one hand, a mature person is likely to be pretty happy with the way they have been living until the moment of transformation and thus wants things to continue as they were before. On the other hand, any scientist appreciates just how important role models were for their entire career and thus wants to continue the tradition and be just such an example for future generations. This is a quandary that is with me now and is likely to require decades to solve. The Nobel Lecture is different from other lectures in that it combines past, present, and future and is given to a diverse audience ranging from the interested school child to the expert colleague. Writing such a lecture down tends to follow the centuries-long tradition of scientific paper writing that can miss some of the freshness of the actual lecture. Faced with the challenge, I have decided to base this written lecture closely on my Nobel talk, using the slides as the Figures. The main test provides a simple narrative, while the figure legends facilitate more-specific comments and discussions.