Changes of the neurotransmitter serotonin but not of hormones during short time music perception
Changes of the neurotransmitter serotonin but not of hormones during short time music perception
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DOI：
10.1007/s004060070031
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发表时间：
2000-06-01
影响因子：
4.7
通讯作者：
Suhr, B
中科院分区：
文献类型：
--
作者：
Evers, S;Suhr, B
我们研究了影响的感知愉快和不愉快的音乐，由健康受试者与心理测量量表，催乳素和促肾上腺皮质激素。此外，神经递质5-羟色胺（5-HT）的中枢神经传递的血小板模型进行了研究。我们没有观察到任何显着的催乳素和促肾上腺皮质激素在不同类型的音乐知觉的变化。然而，与不愉快的音乐相比，血小板的5-HT含量在愉快的音乐感知期间更高，表明在不愉快的音乐期间5-HT的释放增加（748 ng/10（9）血小板对699 ng/10（9）血小板; p < 0.014）。5-HT水平的差异与受试者评定的不愉快评分显著相关。我们的数据表明，感知不愉快的音乐诱导增加释放和减少周边和可能也中央细胞内的5-HT含量。
We studied the impact of the perception of pleasant and unpleasant music, as rated by healthy subjects with a psychometric scale, on the hormones prolactin and ACTH. In addition, the neurotransmitter serotonin (5-HT) was studied using the platelet model for central neurotransmission of 5-HT. We did not observe any significant changes of prolactin and ACTH during the perception of different kinds of music. The 5-HT content of platelets, however, was higher during the perception of pleasant music as compared to the perception of unpleasant music indicating an increased release of 5-HT during unpleasant music (748 ng/10(9) platelets vs. 699 ng/10(9) platelets; p < 0.014). The difference of the 5-HT level was significantly correlated to the score of unpleasantness as rated by the subjects. Our data suggest that perception of unpleasant music induces increased release and decreased peripheral and possibly also central intracellular content of 5-HT.