Intracranial Hemorrhage in the Preterm Infant: Understanding It, Preventing It

Intracranial Hemorrhage in the Preterm Infant: Understanding It, Preventing It
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DOI:
10.1016/j.clp.2009.07.014
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发表时间:
2009-12-01
影响因子:
2.1
通讯作者:
Bassan, Haim
Bassan, Haim
中科院分区:
医学4区
文献类型:
--
作者:
Bassan, Haim

文献摘要

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新生儿成像、脑监测和血流动力学方面的新发现,以及对早产儿颅内出血 (ICH) 相关炎症和遗传机制的更深入了解,正在为创新的早期检测和预防方法创造机会。本文涵盖了早产儿脑出血的范围,包括生发基质脑室内出血、其并发症以及相关现象,例如小脑出血的新出现。本文的总体目的是回顾目前对早产儿脑出血的机制、诊断、结果和治疗的认识;重新审视它们发展的起源;并讨论未来的期望。
New discoveries in neonatal imaging, cerebral monitoring, and hemodynamics, and greater understanding of inflammatory and genetic mechanisms involved in intracranial hemorrhage (ICH) in the preterm infant are creating opportunities for innovative early detection and prevention approaches. This article covers the spectrum of ICH in the preterm infant, including germinal matrix intraventricular hemorrhage, its complications, and associated phenomena, such as the emerging role of cerebellar hemorrhage. The overall aim of this article is to review the current knowledge of the mechanisms, diagnosis, outcome, and management of preterm ICH; to revisit the origins from which they develop; and to discuss future expectations.