Enantioselective chromatographic resolution and one-pot synthesis of enantiomerically pure sulfoxides over a homochiral Zn-organic framework
Enantioselective chromatographic resolution and one-pot synthesis of enantiomerically pure sulfoxides over a homochiral Zn-organic framework
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DOI：
10.1021/ja076276p
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发表时间：
2007-10-31
影响因子：
15
通讯作者：
Fedin, Vladimir P.
中科院分区：
文献类型：
--
作者：
Nuzhdin, Alexey L.;Dybtsev, Danil N.;Fedin, Vladimir P.
烷基芳基亚砜的（R）-和（S）-对映异构体可通过在微孔手性锌 - 有机聚合物上对亚砜的外消旋混合物进行色谱拆分获得，或者通过在一锅法中用H₂O₂同时催化氧化相应的硫化物以及对所得亚砜进行对映选择性色谱拆分来获得。
(R )- and (S )- enantiomers of alkyl aryl sulfoxides can be obtained by chromatographic resolution of the racemic mixtures of the sulfoxides on a microporous homochiral Zn-organic polymer or by simultaneous catalytic oxidation of the corresponding sulfides with H2O2 and enantioselective chromatographic resolution of the resulting sulfoxides in a one-pot process.