Developing the Impact of Vision Impairment-Very Low Vision (IVI-VLV) Questionnaire as Part of the LoVADA Protocol
Developing the Impact of Vision Impairment-Very Low Vision (IVI-VLV) Questionnaire as Part of the LoVADA Protocol
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DOI：
10.1167/iovs.14-14731
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发表时间：
2014-10-01
影响因子：
4.4
通讯作者：
Guymer, Robyn H.
中科院分区：
文献类型：
--
作者：
Finger, Robert P.;Tellis, Betty;Guymer, Robyn H.
目的。设计和评估适合评估严重视力丧失患者的视力相关生活质量 (VRQoL) 的仪器。方法。使用基于原始视力障碍影响 (IVI) 调查问卷的项目库对总共 603 名法定盲人（较好的眼睛视力 < 20/200）进行了访谈，并添加了适合严重视力丧失者的项目。使用因子和拉什分析分三个步骤进行细化和项目减少，以评估心理测量特性，探索关键指标，例如反应类别功能（下限和上限效应）、工具一维性、判别能力以及针对患者能力的项目难度。结果。最终选择了 28 个项目，分为 IVI-VLV 的两个子量表：日常生活活动、行动能力和安全（ADLMS；16 个项目）和情绪健康（EWB；12 个项目）。两个子量表都是一维的，能够可靠地区分至少三个不同水平的 VRQoL，并且项目难度对于评估样本来说是足够的。使用广义线性模型并控制年龄，我们发现只有较差的总体健康状况（P = 0.005 和 P = 0.007）以及同时存在的抑郁和焦虑（P = 0.019 和 P < 0.001）分别与较低的 ADLMS 和 EWB 子量表评分相关。结论。 IVI-VLV 是一种针对严重视力丧失人群的有效且可靠的 VRQoL 测量方法，其测量结果几乎不受参与者自我感知的一般或心理健康状况的影响。 IVI-VLV 可用作尝试恢复视力的试验的结果衡量标准。
PURPOSE. To design and evaluate an instrument appropriate for assessing vision-related quality of life (VRQoL) in persons with severe vision loss.METHODS. A total of 603 legally blind persons (better eye visual acuity of < 20/200) were interviewed using an item pool based on the original Impact of Vision Impairment (IVI) questionnaire, augmented by items appropriate for persons with severe vision loss. Refinement and item reduction was done in three steps using factor and Rasch analysis to assess psychometric properties, exploring key indices, such as response category functioning (floor and ceiling effects), instrument unidimensionality, discriminant ability, and targeting of item difficulty to patient ability.RESULTS. A final pool of 28 items was selected that grouped into two subscales of the IVI-VLV: activities of daily living, mobility, and safety (ADLMS; 16 items) and emotional well-being (EWB; 12 items). Both subscales are unidimensional, able to differentiate reliably between at least three different levels of VRQoL, and item difficulty was adequate for the assessed sample. Using generalized linear models and controlling for age, we found that only poor general health (P = 0.005 and P = 0.007) and concurrent depression and anxiety (P = 0.019 and P < 0.001) were associated with a lower ADLMS and EWB subscale score, respectively.CONCLUSIONS. The IVI-VLV is a valid and reliable VRQoL measure in persons with severe vision loss, and its measurement is almost unaffected by participants' self-perceived general or mental health. The IVI-VLV can be used as an outcome measure in trials attempting sight restoration.