Are coping strategies related to disease outcome in early breast cancer?

Are coping strategies related to disease outcome in early breast cancer?
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DOI:
10.1016/0022-3999(95)00518-8
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发表时间:
1996-03-01
影响因子:
4.7
通讯作者:
Steiner, R
Steiner, R
中科院分区:
医学3区
文献类型:
--
作者:
Buddeberg, C;Sieber, M;Steiner, R

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对107例早期乳腺癌患者进行了连续5 - 6年的手术治疗(乳房切除术或乳房肿瘤切除术)后的应对策略和疾病结果的调查。在3年的调查期间,通过苏黎世和弗莱堡疾病应对问卷(ZQCI,FQCI)对应对进行了多次评估。数据分析显示,应对策略与目标变量“乳腺癌死亡”之间没有显著相关性。然而,术后肿瘤大小(p小于或等于0.01)、阳性组织学淋巴结状态(p小于或等于0.01)与乳腺癌死亡之间存在显著相关性。判别分析的结果还表明,体细胞参数对乳腺癌的病程比心理方面的应对更重要。心理社会变量对癌症结局的作用尚不清楚,有必要在这一领域进行进一步研究。
A consecutive series of 107 women with early breast cancer were investigated for coping strategies and disease outcome 5 to 6 years after primary surgical treatment (mastectomy or lumpectomy). Coping was assessed several times during a 3-year investigation period by the Zurich and Freiburg Questionnaires of Coping with Illness (ZQCI,FQCI). Data analysis revealed no significant correlations between coping strategies and the target variable ''death from breast cancer''. However, significant relations were found between postsurgical tumour size (p less than or equal to 0.01), positive histological node status (p less than or equal to 0.01) and death from breast cancer. The results of a discriminant analysis also indicated that somatic parameters are more important for the course of breast cancer disease than psychological aspects of coping. The role of psychosocial variables for the outcome of cancer disease remains unclear and further studies in this field are necessary.