The European Bioinformatics Institute in 2018: tools, infrastructure and training
The European Bioinformatics Institute in 2018: tools, infrastructure and training
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DOI：
10.1093/nar/gky1124
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发表时间：
2019-01-08
影响因子：
14.9
通讯作者：
Apweiler, Rolf
中科院分区：
文献类型：
--
作者：
Cook, Charles E.;Lopez, Rodrigo;Apweiler, Rolf
欧洲生物信息学研究所（https：//www.ebi.ac.uk/）对世界各地研究人员产生的生命科学数据进行存档、整理和分析，并将这些数据提供给全球重新使用（https：//www.ebi.ac.uk/）。数据量继续呈指数级增长：总原始存储容量现已超过160 PB，我们在保持服务质量的同时管理这些不断增长的数据流。今年，我们提高了计算基础设施的效率，并将我们与全球网络连接的带宽增加了一倍。我们报告了两个新的数据资源，单细胞表达图谱（https：//www.ebi.ac.uk/gxa/sc/），这是表达图谱的一个组成部分;和PDBe-Knowledgebase（https：//www.ebi.ac.uk/pdbe/pdbe-kb），它整理了蛋白质数据库中结构数据的功能注释和预测。此外，Europe PMC（http：//europepmc.org/）在其检索结果中添加了预印本摘要，补充了同行评审出版物的结果。EMBL-EBI拥有超过150种分析生物信息学工具，以补充我们的数据资源。我们通过Web界面以及使用应用程序编程接口以编程方式为用户提供这些工具，同时确保为我们的用户提供最新版本。我们的培训团队在全体员工的支持下，今年继续为全球数千名研究人员提供现场、非现场和基于网络的培训机会。
The European Bioinformatics Institute (https://www.ebi.ac.uk/) archives, curates and analyses life sciences data produced by researchers throughout the world, and makes these data available for re-use globally (https://www.ebi.ac.uk/). Data volumes continue to grow exponentially: total raw storage capacity now exceeds 160 petabytes, and we manage these increasing data flows while maintaining the quality of our services. This year we have improved the efficiency of our computational infrastructure and doubled the bandwidth of our connection to the worldwide web. We report two new data resources, the Single Cell Expression Atlas (https://www.ebi.ac.uk/gxa/sc/), which is a component of the Expression Atlas; and the PDBe-Knowledgebase (https://www.ebi.ac.uk/pdbe/pdbe-kb), which collates functional annotations and predictions for structure data in the Protein Data Bank. Additionally, Europe PMC (http://europepmc.org/) has added preprint abstracts to its search results, supplementing results from peer-reviewed publications. EMBL-EBI maintains over 150 analytical bioinformatics tools that complement our data resources. We make these tools available for users through a web interface as well as programmatically using application programming interfaces, whilst ensuring the latest versions are available for our users. Our training team, with support from all of our staff, continued to provide on-site, off-site and web-based training opportunities for thousands of researchers worldwide this year.