Imaging a full set of optical scattering properties of biological tissue by inverse spectroscopic optical coherence tomography.
Imaging a full set of optical scattering properties of biological tissue by inverse spectroscopic optical coherence tomography.
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DOI：
10.1364/ol.37.004443
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发表时间：
2012-11-01
期刊：
影响因子：
3.6
通讯作者：
Backman V
中科院分区：
文献类型：
--
作者：
Yi J;Backman V
我们在这里开发了一种通过逆光谱光学相干断层扫描（ISOCT）测量和成像完整光学散射特性的方法。组织被建模为具有连续折射率 (RI) 波动的介质，并且这种波动由 RI 相关函数描述。在一阶Born近似下，建立了ISOCT的正演模型。通过测量组织的光学量，包括 OCT 光谱的散射功率 (SP)、定义为散射系数 μs 与后向散射系数 μb 之比的反射反照率 α，我们能够反推导 RI 相关函数并对全套光学散射特性进行成像。
We here develop a method to measure and image the full optical scattering properties by inverse spectroscopic optical coherence tomography (ISOCT). Tissue is modelled as a medium with continuous refractive index (RI) fluctuation and such a fluctuation is described by the RI correlation functions. Under the first-order Born approximation, the forward model is established for ISOCT. By measuring optical quantities of tissue including the scattering power (SP) of the OCT spectrum, the reflection albedo α defined as the ratio of scattering coefficient μs and backscattering coefficient μb, we are able to inversely deduce the RI correlation function and image the full set of optical scattering properties.