SOME RELATIONSHIPS BETWEEN CALORIC RESTRICTION AND BODY WEIGHT IN RAT .1. BODY COMPOSITION, LIVER LIPIDS AND ORGAN WEIGHTS
SOME RELATIONSHIPS BETWEEN CALORIC RESTRICTION AND BODY WEIGHT IN RAT .1. BODY COMPOSITION, LIVER LIPIDS AND ORGAN WEIGHTS
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DOI：
10.1093/jn/74.3.243
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发表时间：
1961-01-01
影响因子：
4.2
通讯作者：
LUCIA, SP
中科院分区：
文献类型：
--
作者：
LEE, M;LUCIA, SP
体重200克的雄性Long-Evans大鼠被喂以不允许体重增加的合成饲料。每天需要的食量逐渐减少，到6周结束时只有原来需要的60%。在限制饮食的26周内，身体脂肪的比例和身体蛋白质在脱脂体重中的比例没有变化。体水出现了一些轻微但显著的变化。在此期间，肝脏总脂、胆固醇和磷脂保持不变。心脏和肾脏的重量不受限制的影响，但肝脏的重量显示出一些变化。结论是，热量需求的适应不是大体成分改变的结果。
Male Long-Evans rats weighing 200 g were fed a synthetic diet in amounts which did not permit an increase in weight. The amount of diet required per day gradually decreased and by the end of 6 weeks it was only 60%; of the original requirement. The proportion of body fat and the body protein as a proportion of fat-free body weight did not change during 26 weeks on the restricted diet. Body water showed some slight but significant changes. Liver total lipids, cholesterol, and phospholipids were constant during this time. The weights of the heart and kidneys were unaffected by restriction but liver weights showed some changes. It is concluded that the caloric-requirement adaptation is not a result of alterations in gross body composition.