Symptom prevalence during menopause and factors associated with symptoms and menopausal age. Results from the Norwegian Hordaland Women's Cohort study
Symptom prevalence during menopause and factors associated with symptoms and menopausal age. Results from the Norwegian Hordaland Women's Cohort study
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DOI：
10.1016/j.maturitas.2011.09.011
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发表时间：
2011-12-01
期刊：
影响因子：
4.9
通讯作者：
Hunskaar, Steinar
中科院分区：
文献类型：
--
作者：
Gjelsvik, Bjorn;Rosvold, Elin O.;Hunskaar, Steinar
目的：描述一个有代表性的挪威女性队列在十年期间绝经过渡期和绝经年龄的症状，分析与症状频率和负担相关的因素以及对自测健康的影响。研究设计：2229名年龄在40-44岁的女性，从挪威Hordaland县的一项全国健康调查中随机选择，随后从1997年到2009年进行了七次邮寄问卷调查。2002年妇女（90%）的数据有资格进行analysis.Results：在纵向分析中，36%的妇女报告每天潮热在一个或多个问卷，而29%没有经历潮热在所有。每日潮热的患病率从41-42岁的2%增加到53-54岁的22%，在55-57岁下降到20%。每日吸烟者报告每日潮热与从不/很少报告潮热的比值比为1.6（1.24-2.10）。与具有大学学位的女性相比，受教育程度最低的女性报告每日潮热的OR = 1.8（1.21-2.56）。症状负担与基线时记录的体育锻炼程度、总体健康感、BMI、家庭收入、产次或初潮年龄无关。该队列中末次月经期（FMP）的平均年龄为51.1（50.9-51.3）岁。吸烟者的平均年龄FMP 0.9年前相比，nonsmokers.Conclusions：每天吸烟和教育水平是独立的危险因素，每天经历更年期症状。体育锻炼程度、BMI、产次或初潮年龄对月经量无显著影响。(C)2011爱思唯尔爱尔兰有限公司保留所有权利。
Objectives: To describe symptoms during the menopausal transition and age at menopause in a representative Norwegian female cohort over a ten year period, to analyze factors associated with frequency and burden of symptoms and influence on self-rated health.Study design: 2229 women aged 40-44 years at inclusion, randomly selected from a national health survey in Hordaland County, Norway, and followed with seven postal questionnaires from 1997 throughout 2009. Data for 2002 women (90%) were eligible for analyses.Results: In a longitudinal analysis, 36% of the women reported daily hot flushes in one or more questionnaires, whereas 29% did not experience hot flushes at all. The prevalence of daily hot flushes increased from 2% at age 41-42 to 22% at age 53-54, decreasing to 20% at age 55-57. The odds ratio for reporting daily hot flushes vs. never/seldom for daily smokers was 1.6(1.24-2.10). Women in the lowest education group had an OR = 1.8 (1.21-2.56) for reporting daily hot flushes compared to women with a university degree. There was no relation between the symptom burden and degree of physical exercise, overall feeling of health, BMI, family income, parity or menarche age as recorded at baseline. The mean age for final menstruation period (FMP) in the cohort was 51.1 (50.9-51.3) years. Smokers had a mean age of FMP 0.9 years earlier compared to the non-smokers.Conclusions: Daily smoking and educational level were independent risk factors for experiencing daily menopausal symptoms. Degree of physical exercise, BMI, parity or menarche age did not have significant influence. (C) 2011 Elsevier Ireland Ltd. All rights reserved.