Deep Brain Stimulation for Substance Use Disorders? An Exploratory Qualitative Study of Perspectives of People Currently in Treatment.
Deep Brain Stimulation for Substance Use Disorders? An Exploratory Qualitative Study of Perspectives of People Currently in Treatment.
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DOI：
10.1097/adm.0000000000001150
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发表时间：
2023-07-01
影响因子：
5.5
通讯作者：
中科院分区：
文献类型：
--
作者：
尽管之前的研究已经讨论了深部脑刺激（DBS）作为药物使用障碍（SUD）的可能治疗方法的前景，并收集了研究人员对其周围可能的伦理问题的看法，但没有人咨询过 SUD 患者本身。我们通过采访具有 SUD 的人来解决这一差距。参与者观看了介绍 DBS 的短视频，然后进行了 1.5 小时的半结构化访谈，了解他们使用 SUD 的经验以及他们对 DBS 作为可能的治疗选择的看法。多名程序员对采访进行了分析，他们反复确定了显着的主题。我们采访了 20 名参与 12 步住院治疗计划的患者（10 名 [50%] 白人/白人、7 名黑人/非裔美国人 [35%]、2 名亚洲人 [10%]、1 名西班牙裔/拉丁裔 [5%] 和 1 名 [5%] 阿拉斯加原住民/美洲印第安人；9 名女性 [45%]、11 名男性 [55%]）。受访者描述了他们目前在疾病过程中面临的各种障碍，这些障碍反映了通常与 DBS 相关的障碍（耻辱、侵入性、维护负担、隐私风险），从而使他们对 DBS 作为未来治疗选择的可能性更加开放。与之前对提供者态度的调查预期相比，患有 SUD 的个体对与 DBS 相关的手术风险和临床负担的重视程度相对较低。这些差异很大程度上源于他们患有致命疾病的经历以及当前治疗方案的局限性。这些发现支持了 DBS 作为 SUD 治疗选择的研究，并得到了 SUD 患者和倡导者的广泛投入。
Although previous studies have discussed the promise of deep brain stimulation (DBS) as a possible treatment for substance use disorders (SUDs) and collected researcher perspectives on possible ethical issues surrounding it, none have consulted people with SUDs themselves. We addressed this gap by interviewing people with SUDs. Participants viewed a short video introducing DBS, followed by a 1.5-hour semistructured interview on their experiences with SUDs and their perspective on DBS as a possible treatment option. Interviews were analyzed by multiple coders who iteratively identified salient themes. We interviewed 20 people in 12-step–based, inpatient treatment programs (10 [50%] White/Caucasian, 7 Black/African American [35%], 2 Asian [10%], 1 Hispanic/Latino [5%], and 1 [5%] Alaska Native/American Indian; 9 women [45%], 11 men [55%]). Interviewees described a variety of barriers they currently faced through the course of their disease that mirrored barriers often associated with DBS (stigma, invasiveness, maintenance burdens, privacy risks) and thus made them more open to the possibility of DBS as a future treatment option. Individuals with SUDs gave relatively less weight to surgical risks and clinical burdens associated with DBS than previous surveys of provider attitudes anticipated. These differences derived largely from their experiences living with an often-fatal disease and encountering limitations of current treatment options. These findings support the study of DBS as a treatment option for SUDs, with extensive input from people with SUDs and advocates.
影响因子：
13.4
作者：
Goering, Sara;Brown, Timothy Emmanuel;McCusker, Darcy;Montes, Natalia;Schonau, Andreas;Versalovic, Erika;Klein, Eran
通讯作者：
Klein, Eran