Biomimetic 4D printing
Biomimetic 4D printing
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DOI：
10.1038/nmat4544
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发表时间：
2016-04-01
期刊：
影响因子：
41.2
通讯作者：
Lewis, Jennifer A.
中科院分区：
文献类型：
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作者：
Gladman, A. Sydney;Matsumoto, Elisabetta A.;Lewis, Jennifer A.
形状变形系统可以在许多领域找到，包括智能纺织品（1），自主机器人（2），生物医学设备（3），药物输送（4）和组织工程（5）。这种系统的天然类似物以植物的感性运动为例，其中各种器官如卷须、苞片、叶子和花通过改变内部膨压来响应环境刺激（如湿度、光或触摸），这导致由组织组成和细胞壁的微结构各向异性控制的动态构象（6-10）。受这些植物系统的启发，我们打印了复合水凝胶结构，该结构编码有局部的、各向异性的溶胀行为，这些溶胀行为由纤维素原纤维沿着规定的四维打印路径的排列控制。当结合最小的理论框架，使我们能够解决设计指定目标形状的对齐模式的逆问题时，我们可以编程制造植物灵感的架构，这些架构在浸入水中时会改变形状，产生复杂的三维形态。
Shape-morphing systems can be found in many areas, including smart textiles(1), autonomous robotics(2), biomedical devices(3), drug delivery(4) and tissue engineering(5). The natural analogues of such systems are exemplified by nastic plant motions, where a variety of organs such as tendrils, bracts, leaves and flowers respond to environmental stimuli (such as humidity, light or touch) by varying internal turgor, which leads to dynamic conformations governed by the tissue composition and microstructural anisotropy of cell walls(6-10). Inspired by these botanical systems, we printed composite hydrogel architectures that are encoded with localized, anisotropic swelling behaviour controlled by the alignment of cellulose fibrils along prescribed four-dimensional printing pathways. When combined with a minimal theoretical framework that allows us to solve the inverse problem of designing the alignment patterns for prescribed target shapes, we can programmably fabricate plant-inspired architectures that change shape on immersion in water, yielding complex three-dimensional morphologies.