Association between the number of injuries sustained and 12-month disability outcomes: evidence from the injury-VIBES study.
Association between the number of injuries sustained and 12-month disability outcomes: evidence from the injury-VIBES study.
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持续的伤害数量与12个月的残疾结局之间的关联：受伤 - 维伯斯研究的证据。
DOI：
10.1371/journal.pone.0113467
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发表时间：
2014
期刊：
影响因子：
3.7
通讯作者：
Rivara FP
中科院分区：
文献类型：
--
作者：
Gabbe BJ;Simpson PM;Lyons RA;Ameratunga S;Harrison JE;Derrett S;Polinder S;Davie G;Rivara FP
确定住院患者受伤后12个月内受伤次数与三项残疾指标之间的关系。来自27，840名因受伤住院的成年（18岁以上）参与者的数据被提取用于验证和改善伤害负担估计（伤害-VIBES）研究的分析。根据持续性损伤的数量，使用改良泊松和线性回归分析分别估计一系列结局（格拉斯哥结局量表扩展版，GOS-E; EQ-5D和12项简明健康调查表身体和精神分量总分，PCS-12和MCS-12）的相对风险和平均差异，并根据年龄、性别和贡献研究进行调整。超过一半（54%）的患者有一个以上的ICD-10身体部位损伤，62%的患者有一种以上的全球疾病负担损伤类型。功能恢复不良（GOS-E<7）和EQ-5D中每个项目报告问题的调整后相对风险随每个额外损伤类型或身体部位的损伤增加5-10%。校正后的平均PCS-12和MCS-12评分随每种额外损伤类型或身体部位的损伤而恶化，分别为1.3-1.5分和0.5分。受伤类型和受伤身体部位的数量与12个月功能和健康状况结果之间存在一致和强烈的关系。现有的解剖损伤严重程度的综合指标，如NISS或ISS，最多只使用三种诊断，可能不足以描述或解释残疾研究中的多发性损伤。未来的研究应考虑多重伤害的影响，以避免低估伤害负担。
To determine associations between the number of injuries sustained and three measures of disability 12-months post-injury for hospitalised patients. Data from 27,840 adult (18+ years) participants, hospitalised for injury, were extracted for analysis from the Validating and Improving injury Burden Estimates (Injury-VIBES) Study. Modified Poisson and linear regression analyses were used to estimate relative risks and mean differences, respectively, for a range of outcomes (Glasgow Outcome Scale-Extended, GOS-E; EQ-5D and 12-item Short Form health survey physical and mental component summary scores, PCS-12 and MCS-12) according to the number of injuries sustained, adjusted for age, sex and contributing study. More than half (54%) of patients had an injury to more than one ICD-10 body region and 62% had sustained more than one Global Burden of Disease injury type. The adjusted relative risk of a poor functional recovery (GOS-E<7) and of reporting problems on each of the items of the EQ-5D increased by 5–10% for each additional injury type, or body region, injured. Adjusted mean PCS-12 and MCS-12 scores worsened with each additional injury type, or body region, injured by 1.3–1.5 points and 0.5 points, respectively. Consistent and strong relationships exist between the number of injury types and body regions injured and 12-month functional and health status outcomes. Existing composite measures of anatomical injury severity such as the NISS or ISS, which use up to three diagnoses only, may be insufficient for characterising or accounting for multiple injuries in disability studies. Future studies should consider the impact of multiple injuries to avoid under-estimation of injury burden.
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DOI：
10.1186/1757-7241-21-42
发表时间：
2013-05-30
期刊：
Scandinavian journal of trauma, resuscitation and emergency medicine
影响因子：
--
作者：
Scivoletto G;Farchi S;Laurenza L;Tamburella F;Molinari M
通讯作者：
Molinari M
影响因子：
3.7
作者：
Gabbe, Belinda J.;Lyons, Ronan A.;Derrett, Sarah
通讯作者：
Derrett, Sarah
影响因子：
168.9
作者：
Murray, Christopher J. L.;Vos, Theo;Lopez, Alan D.
通讯作者：
Lopez, Alan D.
DOI：
10.1016/j.injury.2006.10.026
发表时间：
2007-03-01
影响因子：
2.5
作者：
Holtslag, H. R.;Post, M. W.;Van der Werken, Chr.
通讯作者：
Van der Werken, Chr.
DOI：
10.1016/j.injury.2012.05.008
发表时间：
2012-10-01
影响因子：
2.5
作者：
Ardolino, A.;Sleat, G.;Willett, K.
通讯作者：
Willett, K.