Physical performance and 13.5-year mortality in elderly women
Physical performance and 13.5-year mortality in elderly women
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DOI：
10.1177/1403494812466460
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发表时间：
2013-02-01
影响因子：
3.4
通讯作者：
Bergland, Astrid
中科院分区：
文献类型：
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作者：
Idland, Gro;Engedal, Knut;Bergland, Astrid
目的：研究四种可修改的基于身体机能的测量方法是否能预测300名老年妇女13.5年的死亡率。研究方法：这项前瞻性观察性队列研究随访了300名随机选择的社区居民妇女，基线时平均年龄为80.9岁，为期13.5年。基线体能测量包括：舒适步行速度、计时起身和行走（TUG）、功能性伸展和单腿站立。记录人口统计学和健康测量结果。从国家人口登记处记录死亡日期。拟合考克斯比例风险模型，从基线评估至死亡或删失日期的时间作为因变量。结果：随访时，71%的参与者死亡。除单腿站立外，所有基于性能的测量与13.5年死亡率显著相关。当三个重要的性能测量被包括在相同的多比例风险考克斯模型中时，只有步行速度仍然与死亡率显著独立相关。结论：舒适步行速度、TUG和功能伸展可预测13.5年死亡率，步行速度是死亡率的最强预测因子。筛选老年妇女与性能测量可能有助于确定那些在风险，从而有针对性的干预措施可以应用。
Aims: To examine whether four modifiable physical performance-based measurements predicted 13.5-year mortality in 300 elderly women. Methods: This prospective observational cohort study followed 300 randomly-selected community-dwelling women, with a mean age of 80.9 years at baseline, for 13.5 years. Baseline physical performance measurements were: comfortable walking speed, Timed Up and Go (TUG), functional reach, and one-leg stance. Demographic and health measurements were recorded. Date of death was recorded from the national population registry. Cox proportional hazard models were fitted, with time from baseline assessment to death or censored date as the dependent variable. Results: At follow-up, 71% of the participants had died. All performance-based measurements except one-leg stance were significantly associated with 13.5-year mortality. Only walking speed remained significantly independently associated with mortality when the three significant performance measurements were included in the same multiple proportional hazard Cox model. Conclusions: Comfortable walking speed, TUG and functional reach predicted 13.5-year mortality, and walking speed was the strongest predictor of mortality. Screening elderly women with performance measurements may aid in identifying those at risk and thus targeted interventions may be applied.