On MRI turbulence quantification
On MRI turbulence quantification
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DOI：
10.1016/j.mri.2009.05.004
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发表时间：
2009-09-01
影响因子：
2.5
通讯作者：
Ebbers, Tino
中科院分区：
文献类型：
--
作者：
Dyverfeldt, Petter;Gardhagen, Roland;Ebbers, Tino
以速度波动为特征的湍流伴随着许多形式的心血管疾病，并可能导致其进展和血流动力学后果。一些研究已经调查了湍流对磁共振成像（MRI）信号的影响。定量MRI湍流测量最近已被证明有很大的潜力，在人体心血管流动和工程流的应用。在这篇文章中，潜在的陷阱和MRI湍流测量的误差来源进行了理论和数值研究。概述了适用于湍流定量的数据采集策略。结果表明，MRI湍流测量的内部体素平均速度变化的敏感性是可以忽略不计的，但噪声可能会降低估计，如果湍流编码参数设置不当。研究表明，利用给定扫描时间的不同方法会影响动态范围和噪声导致的湍流估计的不确定性。在这项工作中报告的结果可能是有价值的，在体外和体内研究采用MRI方法的湍流量化。(C)2009 Elsevier Inc. All rights reserved.
Turbulent flow, characterized by velocity fluctuations, accompanies many forms of cardiovascular disease and may contribute to their progression and hemodynamic consequences. Several studies have investigated the effects of turbulence on the magnetic resonance imaging (MRI) signal. Quantitative MRI turbulence measurements have recently been shown to have great potential for application both in human cardiovascular flow and in engineering flow. In this article, potential pitfalls and sources of error in MRI turbulence measurements are theoretically and numerically investigated. Data acquisition strategies suitable for turbulence quantification are outlined. The results show that the sensitivity of MRI turbulence measurements to intravoxel mean velocity variations is negligible, but that noise may degrade the estimates if the turbulence encoding parameter is set improperly. Different approaches for utilizing a given amount of scan time were shown to influence the dynamic range and the uncertainty in the turbulence estimates due to noise. The findings reported in this work may be valuable for both in vitro and in vivo studies employing MRI methods for turbulence quantification. (C) 2009 Elsevier Inc. All rights reserved.