Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic.
Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic.
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DOI：
10.1161/circresaha.110.232678
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发表时间：
2011-03-04
影响因子：
20.1
通讯作者：
Nahrendorf M
中科院分区：
文献类型：
--
作者：
Leuschner F;Nahrendorf M
在改变临床前研究和临床护理的承诺的推动下，心血管分子成像在靶向冠状动脉粥样硬化和心力衰竭方面取得了进展。我们在这里讨论该领域的最新进展，强调分子成像如何促进预防性患者护理，并回顾与冠状动脉和心力衰竭成像相关的具体挑战。实际考虑强调了荧光成像在基础研究中的潜力，并讨论了混合方案，如FMT-CT和PET-MRI。
Motivated by the promise to transform preclinical research and clinical care, cardiovascular molecular imaging has made advances towards targeting coronary atherosclerosis and heart failure. We here discuss recent progress in the field, highlight how molecular imaging may facilitate preventive patient care, and review specific challenges associated with coronary and heart failure imaging. Practical considerations stress the potential of fluorescence imaging for basic research and discuss hybrid protocols such as FMT-CT and PET-MRI.