Elvin A. Kabat (1914-2000).

Elvin A. Kabat (1914-2000).
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埃尔文·卡巴特 (1914-2000)。

DOI:
10.1038/35030291
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发表时间:
2000
期刊:
影响因子:
64.8
通讯作者:
Mage,RG
Mage,RG
中科院分区:
综合性期刊1区
文献类型:
--
作者:
Paul,WE;Mage,RG

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Elvin A. Kabat, who died on 16 June 2000, was a founder of modern immunochemistry. A man of great forthrightness and acerbic wit, he set the standard for immunological science for more than three decades.Starting with his predoctoral work with Michael Heidelberger at Columbia University in New York, from 1933 to 1937, Kabat was a student of carbohydrate chemistry. He had a career-long interest in the structure and immunochemistry of blood-group substances, and determined the chemical basis of the ABO blood groups. This work, along with that of Walter Morgan and Winifred Watkins in Britain, laid the foundations for our current understanding of carbohydrate ‘differentiation’antigens (cell-surface structures that vary according to developmental stage or tissue type) and their roles in cellular interactions.