Intrathecal chemotherapy for leptomeningeal dissemination of medulloblastoma.
Intrathecal chemotherapy for leptomeningeal dissemination of medulloblastoma.
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鞘内化疗治疗髓母细胞瘤的软脑膜播散。
DOI：
10.1159/000120013
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Wilson,CB
中科院分区：
文献类型：
--
作者：
Edwards,MS;Levin,VA;Seager,ML;Wilson,CB
尽管进行了充分的全身化疗，髓母细胞瘤的脑脊液播散仍会发生，并且除非在初次诊断时存在，否则会在病程晚期发生。植入 Ommaya 储库的鞘内化疗可产生短期效益。我们在此报告针对髓母细胞瘤软脑膜播散的鞘内化疗方案和结果。
Cerebrospinal fluid dissemination of medulloblastoma occurs despite adequate systemic chemotherapy, and unless it is present at the time of initial diagnosis, occurs late in the course of the disease. Intrathecal chemotherapy with an implanted Ommaya reservoir can produce short-term benefit. We report here our protocol for and the results of intrathecal chemotherapy for leptomeningeal dissemination of medulloblastoma.