Hypoxia signaling in hematopoietic stem cells: a double-edged sword.
Hypoxia signaling in hematopoietic stem cells: a double-edged sword.
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造血干细胞中的缺氧信号:一把双刃剑。
DOI:
10.1016/j.stem.2010.08.006
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发表时间:
2010
期刊:
影响因子:
23.9
通讯作者:
Kamil R. Kranc
中科院分区:
文献类型:
--
作者:
Patrick J. Pollard;Kamil R. Kranc
Although hematopoietic stem cells (HSCs) reside in hypoxic niches, the significance of hypoxia signaling in HSCs remains unclear. In this issue ofCell Stem Cell, Takubo et al. (2010) and Simsek et al. (2010) demonstrate that hypoxia regulates the metabolic state of HSCs and protects their integrity by controlling HIF-1α.
影响因子:
23.9
作者:
Simsek T;Kocabas F;Zheng J;Deberardinis RJ;Mahmoud AI;Olson EN;Schneider JW;Zhang CC;Sadek HA
通讯作者:
Sadek HA