The nuclear envelope: Its breakdown and fate in mammalian oogonia and oocytes

The nuclear envelope: Its breakdown and fate in mammalian oogonia and oocytes
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核膜:哺乳动物卵原细胞和卵母细胞的分解和命运

DOI:
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发表时间:
1972
期刊:
The Anatomical Record
影响因子:
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通讯作者:
R. Donahue
R. Donahue
中科院分区:
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文献类型:
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作者:
D. Szőllősi;P. Calarco;R. Donahue

文献摘要

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The dissolution of the nuclear envelope (NE) has been studied ultrastructurally in mouse oocytes maturing in vitro. NE breakdown begins with the undulation of the nuclear envelope followed by the disappearance of nuclear pores. Subsequently, extensive NE convolutions, possibly caused by impinging microtubules, result in the apposition of adjacent NE segments, the appearance of breaks and the formation of NE doublets. Doublets may also be formed by the apposition of intranuclear cisternae to the inner leaflet of the NE. Nuclear envelope breakdown in mouse oocytes takes approximately three and one‐half hours in vitro.