CDPK-mediated signalling pathways: specificity and cross-talk
CDPK-mediated signalling pathways: specificity and cross-talk
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DOI：
10.1093/jxb/erh008
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发表时间：
2004-01-01
影响因子：
6.9
通讯作者：
Jones, JDG
中科院分区：
文献类型：
--
作者：
Ludwig, AA;Romeis, T;Jones, JDG
植物不断暴露于环境变化，必须整合各种生物和非生物胁迫刺激。钙依赖性蛋白激酶 (CDPK) 是植物响应这些胁迫时 Ca2+ 通量的重要传感器。 CDPK 由多基因家族编码，这些基因的表达水平在整个发育过程中在空间和时间上受到控制。此外，CDPK 基因的一个子集会对外部刺激做出反应。生化证据支持 CDPK 参与应激条件下信号转导的观点。此外，功能丧失和功能获得研究表明，导致寒冷、盐、干旱或病原体抗性的信号通路是由特定的 CDPK 亚型介导的。
Plants are constantly exposed to environmental changes and have to integrate a variety of biotic and abiotic stress stimuli. Calcium-dependent protein kinases (CDPKs) are implicated as important sensors of Ca2+ flux in plants in response to these stresses. CDPKs are encoded by multigene families, and expression levels of these genes are spatially and temporally controlled throughout development. In addition, a subset of CDPK genes responds to external stimuli. Biochemical evidence supports the idea that CDPKs are involved in signal transduction during stress conditions. Furthermore, loss-of-function and gain-of-function studies revealed that signalling pathways leading to cold, salt, drought or pathogen resistance are mediated by specific CDPK isoforms.