Prognosis in Patients with Transient Ischemic Attacks
Prognosis in Patients with Transient Ischemic Attacks
复制标题
短暂性脑缺血发作患者的预后
DOI：
10.1161/01.str.4.4.666
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发表时间：
1973
期刊：
影响因子：
8.3
通讯作者：
R. Hassanein
中科院分区：
文献类型：
--
作者：
D. Ziegler;R. Hassanein
在至少三年的时间内，通过间隔定量发作次数和通过残疾评分确定144例短暂性脑缺血发作患者的预后。在研究开始时，没有患者患有神经功能残疾。对93例患者进行了全头颈部血管造影。144名患者中有7人在三年期结束时死亡，其中5人死于中风。17例患者（15.6%）在三年内发展为持续性神经功能障碍，颈动脉发作患者的平均残疾评分远高于基底动脉发作患者。颈动脉组和基底动脉组的累积发作次数在前18个月稳步上升，基底动脉组的发作次数要多得多。颈动脉组的发病率在18个月后趋于平稳。在一段时间内，攻击的性质往往是一致的。28%的基底动脉发作患者和12.5%的颈动脉发作患者在血管造影中显示颈动脉狭窄。颈动脉狭窄与随后的神经功能障碍相关的研究表明，只有当颈动脉狭窄超过70%时，
The prognosis on 144 patients with transient ischemic attacks was determined over a minimum period of three years by quantitating, at intervals, the number of attacks and also the neurological disability by means of a disability score. No patients had neurological disability at the initiation of the study. Total cervicocephalic angiography was performed on 93 patients. Seven of the 144 patients were deceased at the end of the three-year period, five of them due to strokes. Seventeen patients (15.6%) developed persistent neurological disability during the three years, with the mean disability score being much higher for the patients with carotid attacks than those with basilar attacks. The cumulative number of attacks in both carotid and basilar groups rose steadily in the first 18 months, with a much larger number of attacks occurring in the basilar group. The attack rate leveled off after 18 months in the carotid group. Attacks tended to be consistent in nature over a period of time. Twenty-eight percent of those patients with basilar attacks and 12.5% of those patients with carotid attacks showed carotid stenosis on angiography. Study of carotid stenosis associated with subsequent neurological disability revealed that increased risk occurred only when carotid stenosis was more than 70%