MECHANISMS OF ROD CONE INTERACTION - EVIDENCE FROM CONGENITAL STATIONARY NIGHTBLINDNESS
MECHANISMS OF ROD CONE INTERACTION - EVIDENCE FROM CONGENITAL STATIONARY NIGHTBLINDNESS
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DOI：
10.1016/0042-6989(88)90107-1
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发表时间：
1988-01-01
期刊：
影响因子：
1.8
通讯作者：
DERLACKI, DJ
中科院分区：
文献类型：
--
作者：
ALEXANDER, KR;FISHMAN, GA;DERLACKI, DJ
暗适应视杆系统可以提高用于闪烁检测的视锥介导阈值以及用于检测色调的阈值。我们研究了这两种类型的杆锥相互作用在两个人先天性静止，夜盲症（CSNB），视网膜疾病，其中杆外段功能是完整的，但在视网膜内的杆信号的传输发生缺陷。这两种类型的视杆-视锥相互作用受到视网膜病理学的不同影响;视杆-视锥闪烁相互作用是正常的，但视杆-视锥色调相互作用不存在。这些结果提供的证据表明，尽管这两种类型的杆锥相互作用的适应特性的相似之处，它们是由不同的视觉机制介导的。
The dark-adapted rod system can elevate cone-mediating thresholds for flicker detection as well as thresholds for the detection of hue. We examined these two types of rod-cone interactions in two individuals with congenital stationary, nightblindness (CSNB), a retinal disorder in which rod outer segment function is intact, but in which a defect occurs in the transmission of rod signals within the retina. The two types of rod-cone interaction were differentially affected by the retinal pathology; the rod-cone flicker interaction was normal, but the rod-cone hue interaction was absent. These results provide evidence that, despite similarities in the adaptational properties of these two types of rod-cone interaction, they are mediated by different visual mechanisms.