Comparison of Cerebral Oxygen Saturation and Cerebral Perfusion Computed Tomography in Cerebral Blood Flow in Patients with Brain Injury
Comparison of Cerebral Oxygen Saturation and Cerebral Perfusion Computed Tomography in Cerebral Blood Flow in Patients with Brain Injury
复制标题
DOI：
10.1007/978-1-4939-3023-4_18
复制
发表时间：
2016-01-01
期刊：
影响因子：
--
通讯作者：
Grigoryeva, Vera
中科院分区：
文献类型：
--
作者：
Trofimov, Alexey O.;Kalentiev, George;Grigoryeva, Vera
本研究的目的是确定脑外伤患者脑组织氧饱和度与脑血容量的关系。本文对25例外伤性脑损伤患者进行了脑灌注CT检查，同时用近红外血氧仪测定了SctO（2）水平。受伤者的平均年龄为34.5 +/- 15.6岁（15-65岁）; 14名男子，11名妇女。损伤严重度评分（ISS）值为44.4 +/- 9.7（范围25-81）。研究前的格拉斯哥昏迷评分（GCS）平均值为10.6 ± 2.1（范围5-13）。SctO（2）范围为51 - 89%，平均62 +/-8.2%。脑血容量（CBV）值为2.1 ± 0.67 ml/100 g（最小值1.1;最大值4.3 ml/100 g）。脑血流量（CBF）为31.99 +/- 13.6 ml/100 g x min。平均通过时间（MTT）值为5.7 +/- 4.5 s（min 2.8; max 34.3 s）。达峰时间（TTP）为22.2 +/- 3.1 s。SctO（2）水平与脑血容量（CBV）水平之间存在统计学显著相关性（R = 0.9; p< 0.000001）。在脑组织氧合和脑灌注的其他参数之间没有发现其他显著的相关性。
The purpose of this study was to determine the relationship between cerebral tissue oxygen saturation and cerebral blood volume in patients with traumatic brain injury. Perfusion computed tomography of the brain was performed in 25 patients with traumatic brain injury together with simultaneous SctO(2) level measurement using cerebral near-infrared oxymetry. The mean age of the injured persons was 34.5 +/- 15.6 years (range 15-65); 14 men, 11 women. The Injury Severity Score (ISS) values were 44.4 +/- 9.7 (range 25-81). The Glasgow Coma Score (GCS) mean value before the study was 10.6 +/- 2.1 (range 5-13). SctO(2) ranged from 51 to 89 %, mean 62 +/- 8.2 %. Cerebral blood volume (CBV) values were 2.1 +/- 0.67 ml/100 g (min 1.1; max 4.3 ml/100 g). Cerebral blood flow (CBF) was 31.99 +/- 13.6 ml/100 g x min. Mean transit time (MTT) values were 5.7 +/- 4.5 s (min 2.8; max 34.3 s). The time to peak (TTP) was 22.2 +/- 3.1 s. A statistically significant correlation was found between SctO(2) level and cerebral blood volume (CBV) level (R = 0.9; p< 0.000001). No other significant correlations were found between brain tissue oxygenation and other parameters of brain perfusion.