The relationship between area poverty rate and site-specific cancer incidence in the United States.

The relationship between area poverty rate and site-specific cancer incidence in the United States.
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DOI:
10.1002/cncr.28632
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发表时间:
2014-07-15
期刊:
影响因子:
6.2
通讯作者:
Henry, Kevin A.
Henry, Kevin A.
中科院分区:
医学1区
文献类型:
--
作者:
Boscoe, Francis P.;Johnson, Christopher J.;Sherman, Recinda L.;Stinchcomb, David G.;Lin, Ge;Henry, Kevin A.

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在美国,社会经济地位和癌症发病率之间的关系传统上并不是基于人口的癌症监测系统的重点。2005年至2009年期间,来自16个州和洛杉矶的近300万例肿瘤被诊断为基于诊断时居民普查区的贫困率的4组之一。最高至最低贫困类别的性别特异性风险比使用泊松回归进行测量,调整年龄和种族,39个癌症部位。对于所有地点,癌症发病率与贫困之间的关联可以忽略不计;然而,39个癌症地点中有32个与贫困显着相关(14个正相关,18个负相关)。其中19个地点在所有4个贫困类别中的风险单调增加或减少。与较高贫困程度相关性最强的部位是卡波西肉瘤、喉、子宫颈、阴茎和肝脏;与较低贫困程度相关性最强的部位是黑色素瘤、甲状腺、其他非上皮性皮肤和睾丸。与贫困程度较高的地区相比,贫困程度较低的地区发病率较低,死亡率较高。这些研究结果表明,在国家癌症监测中纳入社会经济地位的措施具有重要意义和相关性。Cancer 2014;120:2191-2198.© 2014作者。出版社:Wiley Periodicals,Inc.代表美国癌症协会大多数癌症部位表现出与地区贫困率的显着关联。与较低贫困程度相关的人相比,与较高贫困程度相关的人发病率较低,但死亡率较高。
The relationship between socioeconomic status and cancer incidence in the United States has not traditionally been a focus of population-based cancer surveillance systems. Nearly 3 million tumors diagnosed between 2005 and 2009 from 16 states plus Los Angeles were assigned into 1 of 4 groupings based on the poverty rate of the residential census tract at time of diagnosis. The sex-specific risk ratio of the highest-to-lowest poverty category was measured using Poisson regression, adjusting for age and race, for 39 cancer sites. For all sites combined, there was a negligible association between cancer incidence and poverty; however, 32 of 39 cancer sites showed a significant association with poverty (14 positively associated and 18 negatively associated). Nineteen of these sites had monotonic increases or decreases in risk across all 4 poverty categories. The sites most strongly associated with higher poverty were Kaposi sarcoma, larynx, cervix, penis, and liver; those most strongly associated with lower poverty were melanoma, thyroid, other nonepithelial skin, and testis. Sites associated with higher poverty had lower incidence and higher mortality than those associated with lower poverty. These findings demonstrate the importance and relevance of including a measure of socioeconomic status in national cancer surveillance. Cancer 2014;120:2191–2198. © 2014 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. A majority of cancer sites exhibit significant associations with area poverty rates. Those associated with higher poverty had lower incidence but higher mortality than those associated with lower poverty.
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