Competing risks of heart failure with preserved ejection fraction in diabetic patients
Competing risks of heart failure with preserved ejection fraction in diabetic patients
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DOI：
10.1093/eurjhf/hfr019
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发表时间：
2010-09
影响因子：
18.2
通讯作者：
Yasuharu Takeda;Y. Sakata;T. Mano;T. Ohtani;D. Kamimura;S. Tamaki;Y. Omori;Y. Tsukamoto;Y. Aizawa;I. Komuro;Kazuhiro Yamamoto
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文献类型：
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作者：
Yasuharu Takeda;Y. Sakata;T. Mano;T. Ohtani;D. Kamimura;S. Tamaki;Y. Omori;Y. Tsukamoto;Y. Aizawa;I. Komuro;Kazuhiro Yamamoto
射血分数保留性心力衰竭（HFpEF）的患病率在过去二十年中有所增加，糖尿病（DM）经常与HFpEF相关。虽然已经证明HFpEF患者通常会出现左心室（LV）舒张和血管功能异常，但在DM患者中，无症状阶段如何进展为症状性HFpEF仍有待临床阐明。我们的目的是确定与糖尿病患者HFpEF事件相关的风险因素，并评估LV舒张和顺应性对HFpEF发展的贡献。
The prevalence of heart failure with preserved ejection fraction (HFpEF) has increased in the past two decades, and diabetes mellitus (DM) is frequently associated with HFpEF. Although it has been demonstrated that left ventricular (LV) diastolic and vascular functional abnormalities are generally observed in HFpEF, it remains to be clinically elucidated how an asymptomatic stage progresses to symptomatic HFpEF in DM patients. We aimed to identify risk factors associated with incident HFpEF in DM patients and to evaluate the contribution of LV relaxation and compliance to the development of HFpEF.