A longitudinal study of the biometric and refractive changes in full-term infants during the first year of life
A longitudinal study of the biometric and refractive changes in full-term infants during the first year of life
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DOI：
10.1016/s0042-6989(01)00169-9
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发表时间：
2001-09-01
期刊：
影响因子：
1.8
通讯作者：
Charman, WN
中科院分区：
文献类型：
--
作者：
Pennie, FC;Wood, ICJ;Charman, WN
对20名足月婴儿（男10名，女10名）出生后第一年（平均年龄4-53周）眼轴尺寸和屈光度的变化进行超声和视网膜镜观察。通过混合模型回归分析，发现轴向长度随时间的变化最好用二次表达式来描述（AL = 17.190 + 0.128x - 0.0013x(2)，其中AL为轴向长度，单位为mm， x为年龄，单位为周），而前房深度呈线性变化（ACD = 2.619 + 0.018x，其中ACID为前房深度，单位为mm）：晶状体厚度基本不变。在第一年的大部分时间里，球面等效屈光度显示远视的稳定下降（SER = 2.982 - 0.032x，其中SER为屈光度中的球面等效屈光度），散光也有减少的趋势。全年平均远视屈光不正与相应的眼轴长度呈负相关（SER = 12.583 +/- 0.541AL），但个别受试者明显偏离这一模式。这些结果与正都市化的概念有关。2001爱思唯尔科学有限公司版权所有。
Changes in ocular axial dimensions and refraction were followed longitudinally, using ultrasonography and retinoscopy, during the first year of life (mean ages 4-53 weeks) of a group of 20 full-term infants (10 male, 10 female). Using a mixed-model regression analysis, axial length changes as a function of time were found to be best described by a quadratic expression (AL = 17.190 + 0.128x - 0.0013x(2), where AL is the axial length in mm and x is the age in weeks), while anterior chamber depth changed linearly (ACD = 2.619 + 0.018x, where ACID is the anterior chamber depth in mm): lens thickness was essentially constant. Spherical equivalent refraction through most of the first year showed a steady reduction in hypermetropia (SER = 2.982 - 0.032x, where SER is the spherical equivalent refraction in dioptres): astigmatism also tended to diminish. Mean hyperopic refractive errors through the year were negatively correlated with corresponding axial lengths (SER = 12.583 +/- 0.541AL), but some individual subjects showed marked departures from this pattern. These results are discussed in relation to concepts of emmetropization. (C) 2001 Elsevier Science Ltd. All rights reserved.