Staphylococcus lugdunensis:: An emerging cause of ventriculoperitoneal shunt infections

Staphylococcus lugdunensis:: An emerging cause of ventriculoperitoneal shunt infections
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DOI:
10.1159/000050405
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发表时间:
2001-09-01
影响因子:
0.7
通讯作者:
Shulman, ST
Shulman, ST
中科院分区:
医学4区
文献类型:
--
作者:
Elliott, SP;Yogev, R;Shulman, ST

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鲁氏葡萄球菌是1988年首次报道的一种凝固酶阴性葡萄球菌,是一种在成人中具有相当强致病能力的微生物。与其他凝固酶阴性葡萄球菌的懒惰表现特征不同,卢顿葡萄球菌的感染类似于金黄色葡萄球菌的攻击行为。虽然这种微生物是从成人的各种感染中分离出来的,但它是儿童感染的一种非常罕见的原因。我们描述了头两例由卢顿链球菌引起的脑室-腹膜分流感染的儿科患者。这些病例表明,凝固酶阴性葡萄球菌应该被鉴定到物种水平,如果卢顿葡萄球菌被鉴定出来,与其他凝固酶阴性葡萄球菌分流感染相比,应该有更高的发病率。卢顿沙门氏菌感染推荐较长疗程的治疗。版权所有(C)2001 S.Karger AG,巴塞尔。
Staphylococcus lugdunensis, a coagulase-negative staphylococcus first described in 1988, has gained recognition as an organism with considerable pathogenic capability in adults. In contrast to the indolent presentation characteristic of other coagulase-negative staphylococci, S. lugdunensis infections resemble the aggressive behavior of Staphylococcus aureus. Although the organism has been isolated from a wide variety of infections in adults, it is a very rare cause of pediatric infections. We describe the first two pediatric patients who developed ventriculoperitoneal shunt infections caused by S. lugdunensis. These cases suggest that coagulase-negative staphylococci should be identified to the species level and that, if S. lugdunensis is identified, greater morbidity compared to that associated with other coagulase-negative staphylococcal shunt infections should be anticipated. A longer course of therapy is recommended for S. lugdunensis infections. Copyright (C) 2001 S. Karger AG, Basel.