A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data
A systematic approach for evaluating the quality of experimental toxicological and ecotoxicological data
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DOI：
10.1006/rtph.1996.1076
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发表时间：
1997-02-01
影响因子：
3.4
通讯作者：
Tillmann, U
中科院分区：
文献类型：
--
作者：
Klimisch, HJ;Andreae, M;Tillmann, U
描述了数据质量的评价及其在危害和风险评估中的使用作为一种系统方法。提出了数据的可靠性、相关性和充分性的定义。可靠性分为四类。制定了与可靠性分类的国际测试标准有关的标准。提出了一种评估可靠性的系统文档，特别是在IUCLID数据库中使用。这一方法旨在协调全世界的数据评价过程。它可以帮助专家进行后续评估，并应增加评估的清晰度。(C) 1997学术出版社。
The evaluation of the quality of data and their use in hazard and risk assessment as a systematic approach is described. Definitions are proposed for reliability, relevance, and adequancy of data. Reliability is differentiated into four categories. Criteria relating to international testing standards for categorizing reliability are developed. A systematic documentation of evaluating reliability especially for use in the IUCLID database is proposed. This approach is intended to harmonize data evaluation processes worldwide. It may help the expert in subsequent assessments and should increase the clarity of evaluation. (C) 1997 Academic Press.