T1-Weighted-SPACE Dark Blood Whole Body Magnetic Resonance Angiography (DB-WBMRA): Initial Experience

T1-Weighted-SPACE Dark Blood Whole Body Magnetic Resonance Angiography (DB-WBMRA): Initial Experience
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DOI:
10.1002/jmri.22049
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发表时间:
2010-02-01
影响因子:
4.4
通讯作者:
Rajagopalan, Sanjay
Rajagopalan, Sanjay
中科院分区:
医学2区
文献类型:
--
作者:
Mihai, Georgeta;Chung, Yiu-Cho;Rajagopalan, Sanjay

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目的:评价使用不同翻转角演化优化对比度的深色血液快速自旋回波(FSE)T1加权采样完美性的可行性(T1 w-SPACE)序列在评估从颅外颈动脉到腘动脉的全身动脉壁信息中的应用。28名受试者接受了无对比剂、暗血全身磁共振血管造影(DB-WBMRA)使用针对每个单独站点优化的T1 w-SPACE序列:颈动脉。胸主动脉腹主动脉和大腿/股浅动脉(SFA)。评价了图像质量/血管壁可视化和四个工作站成像所需的时间。两名观察员检查血管壁描绘的再现性进行定量测量,在注册的初始和重复研究(6名受试者)的血管壁和管腔面积在17个位置沿着的动脉trees.Results:在25的28个扫描的主题,黑暗的血液动脉图像采集约1小时的总成像时间允许全身动脉血管壁可视化。结论:应用T1 w-SPACE进行DB-WBMRA是可行的,具有较高的可靠性。
Purpose: To evaluate the feasibility of the dark blood fast spin echo (FSE) T1-weighted-Sampling Perfection with Application of optimized Contrasts using different flip angle Evolution (T1w-SPACE) sequence in assessing whole body arterial wall information from the extracranial carotids to the popliteal artery.Materials and Methods: Twenty-eight subjects were subjected to noncontrast, dark blood whole body magnetic resonance angiography (DB-WBMRA) using a T1w-SPACE sequence optimized for each of the individual stations: carotid artery. thoracic aorta. abdominal aorta. and thigh/superficial femoral artery (SFA). Image quality/vessel wall visualization and the time required to image the four stations were evaluated. Two observers checked the reproducibility of vessel wall depiction by performing quantitative measurements in registered initial and repeat studies (six subjects) of vessel wall and lumen area at 17 locations along the arterial tree.Results: In 25 of the 28 scanned subjects, dark blood arterial images acquired in approximately 1 hour total imaging time allowed whole body arterial vessel wall visualization. Quantitative measurements showed high correlation between the initial and repeat studies for each of the observers as well as high interobserver reproducibility (r > 0.95; P < 0.01).Conclusion: DB-WBMRA using T1w-SPACE is feasible and can be performed with a high degree of reliability.