Simulation of the Second-Harmonic Ultrasound Field in Heterogeneous Soft Tissue Using a Mixed-Domain Method.
Simulation of the Second-Harmonic Ultrasound Field in Heterogeneous Soft Tissue Using a Mixed-Domain Method.
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使用混合域方法模拟异质软组织中的二次谐波超声场。
DOI：
10.1109/tuffc.2019.2892753
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Jing,Yun
中科院分区：
文献类型：
--
作者：
Gu,Juanjuan;Jing,Yun
介绍了一种用于模拟弱非均匀介质中二次谐波声场的混合域方法(MDM)，称为频率特定MDM(FSMDM)。基于拟线性理论，推导了二次谐波的控制方程。声速、非线性系数和衰减系数都是方程中的空间变化函数。首先用FSMDM求解基频压力场，然后用它作为二次谐波方程的源项。用FSMDM再次求解该方程，即可快速得到二次简谐压力场。为了系统地验证所提出的方法，对五个二维案例进行了研究，其中一个案例具有真实的人体组织图。使用先前开发的瞬时MDM的结果作为基准解决方案。比较表明，这两种方法在所有情况下都给出了相似的结果。更重要的是，FSMDM比瞬变MDM有一个关键的优势，它可以快两个数量级。
A mixed-domain method (MDM) dubbed frequency-specific MDM (FSMDM) is introduced for the simulation of the second-harmonic ultrasound field in weakly heterogeneous media. The governing equation for the second harmonics is derived based on the quasi-linear theory. The speed of sound, nonlinear coefficient, and attenuation coefficient are all spatially varying functions in the equation. The fundamental frequency pressure field is first solved by the FSMDM and it is subsequently used as the source term for the second-harmonics equation. This equation can be again solved by the FSMDM to rapidly obtain the second-harmonic pressure field. Five 2-D cases, including one with a realistic human tissue map, are studied to systematically verify the proposed method. Results from the previously developed transient MDM are used as the benchmark solutions. Comparisons show that the two methods give similar results for all cases. More importantly, the FSMDM has a crucial advantage over the transient MDM in that it can be two orders of magnitude faster.