Psychologic factors and risk of mortality after spinal cord injury.

Psychologic factors and risk of mortality after spinal cord injury.
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DOI:
10.1016/j.apmr.2008.10.014
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发表时间:
2009-04
影响因子:
4.3
通讯作者:
Reed, Karla
Reed, Karla
中科院分区:
医学1区
文献类型:
--
作者:
Krause, James S.;Carter, Rickey;Zhai, Yusheng;Reed, Karla

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我们的目标是确定两种不同的心理结构(人格和人生目的(PIL))与脊髓损伤(SCI)患者早期死亡风险之间的关系。前瞻性队列研究,收集了 1997 年底和 1998 年初的健康数据,并于 2005 年 12 月确定了死亡状况。美国东南部的一家大型康复医院。患有创伤性 SCI 的成人 (N=1386),受伤后至少 1 年。不适用。我们首先评估单个心理预测因子(总共 6 个量表)的显着性,同时使用 Cox 比例风险模型控制传记和伤害预测因子,随后基于一组最佳心理变量构建了一个综合模型。整个样本中总共观察到 224 例(16.2%)死亡。由于数据缺失,最终统计模型中的死亡总人数(1128 名参与者)减少至 164 人。在调整了传记和伤害因素的模型中,所有 6 个心理因素均具有统计显着性,而最终的综合模型中仅保留了 3 个心理因素,包括 2 个人格量表(感觉寻求、神经质-焦虑)和 PIL 量表。与仅具有传记和损伤变量的模型相比,最终的综合模型仅略微改善了总体生存预测,因为伪 R2 从 0.121 增加到 0.129,一致性从 0.730 增加到 0.747。结果证实了心理因素对于 SCI 后生存的重要性。
Our objective was to identify the association of 2 distinct psychological constructs, personality and purpose in life (PIL), with risk of early mortality among persons with spinal cord injury (SCI). Prospective cohort study with health data collected in late 1997 and early 1998 and mortality status ascertained in December 2005. A large rehabilitation hospital in the Southeastern United States. Adults (N=1386) with traumatic SCI, at least 1 year post-injury. Not applicable. We first evaluated the significance of a single psychological predictor (a total of 6 scales) while controlling for biographic and injury predictors using Cox proportional hazards modeling and subsequently built a comprehensive model based on an optimal group of psychological variables. There were a total of 224 (16.2%) observed deaths in the full sample. The total number of deaths was reduced to 164 in the final statistical model (out of 1128 participants) due to missing data. All 6 psychological factors were statistically significant in the model that was adjusted for biographic and injury factors, whereas only 3 psychological factors were retained in the final comprehensive model, including 2 personality scales (Sensation Seeking, Neuroticism-Anxiety) and the PIL scale. The final comprehensive model only modestly improved the overall prediction of survival compared to the model with only biographic and injury variables, as the pseudo-R2 increased from 0.121 to 0.129 and the concordance increased from 0.730 to 0.747. The results affirm the importance of psychological factors in relation to survival after SCI.
DOI: 10.1016/j.apmr.2007.11.062
发表时间: 2008-08
影响因子: 4.3
作者:
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影响因子: 4.3
作者:
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