Improved survival following massive transfusion in patients who have undergone trauma
Improved survival following massive transfusion in patients who have undergone trauma
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DOI：
10.1001/archsurg.134.9.964
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发表时间：
1999-09-01
影响因子：
--
通讯作者：
Wilson, SE
中科院分区：
文献类型：
--
作者：
Cinat, ME;Wallace, WC;Wilson, SE
Hypothesis: Survival following massive transfusion in patients who have undergone trauma has improved during the past 10 years.Design: Retrospective cohort study.Setting: Academic level I trauma center in an urban community.Patients: All patients who underwent trauma and who received greater than 50 U of packed red blood cells or whole blood in the 48 hours following admission to the emergency department.Interventions: Data were obtained from blood bank records, the trauma registry, patient medical records, and hospital purchasing records. Patients were divided into 2 groups for comparison (early [1988-1992] and late [1993-1997] periods).Main Outcome Measures: Survival and changes in trauma care provision.Results: Survival following massive transfusion in patients who have undergone trauma has significantly increased during the past 10 years (16% vs 45%, early vs late period, P=.03). Factors associated with poor outcome included male sex, major vascular injury, high Injury Severity Score, severe acidosis, prolonged hypotension, refractory hypothermia, and decreased use of platelet transfusion (all P
